Daravit Tonic

Daravit Tonic

Brand Name

Daravit Tonic

Therapeutic Class


Dosage Form, Composition & NAFDAC Registration Number (NRN)

Syrup (NRN:04-5031): Vitamins, minerals, iron.


Ferrous gluconate is a form of the mineral iron used metabolically in the formation of haemoglobin and necessary for the oxidation process of living tissue. It is used as a dietary supplement, and to prevent and treat iron deficiency anaemia. It is less irritating to the gastrointestinal tract as compared to Ferrous sulphate.

VitaminB12 (Cyanocobalamin) is essential for growth, cell reproduction, hematopoiesis and nucleic acid synthesis.
Folic acid is essential for nucleoprotein synthesis and maintenance of normal erythropoiesis.
Water soluble vitamins namely B1 (Thiamine), B2 (Riboflavin), B6 (Pyridoxine) and Nicotinamide (Vitamin B3) are vital for the normal metabolism in the body.
Vitamin B1 (Thiamine), combines with ATP to form thiamine pyrophosphate, a co-enzyme. Its role in carbohydrate metabolism is the decarboxylation of pyruvic and alpha beta acid.
Vitamin B2 (Riboflavin), functions in the body as a co-enzyme which plays a vital metabolic role in numerous tissue respiratory systems.
Nicotinamide (Niacinamide) or vitamin B3 is required for lipid metabolism, tissue respiration and glycogenolysis.
Vitamin B6 (Pyridoxine Hydrochloride) acts as a co-enzyme in the metabolism of protein, carbohydrates and fat. In protein metabolism, it participates in the decarboxylation of amino acids and conversion of tryptophan to niacin. Vitamin B6 is also responsible for the breakdown of glycogen to glucose-1-phosphate.
Lysine is an essential amino acid in the daily diet necessary for the formation of new body proteins for growth and repair of tissue.
Zinc sulphate is an essential element of nutrition. It is a constituent of most enzyme systems and is necessary for growth of tissues. It plays a crucial role during pregnancy and lactation. It is essential for normal embryogenesis and foetal growth. Prevents Intrauterine Growth Retardation (IUGR) and congenital malformations. Adequate serum concentrations of zinc is necessary for protein and nucleic acid synthesis during haemoglobin formation. It is also helpful in stabilizing cell membranes, wound healing and in improving sense of taste in expectant mothers.


Daravit Day to Day Family Tonic is indicated in iron deficiency anaemia, anaemia of pregnancy; lack of appetite and fatigue.


Haemachromatosis, haemosiderosis, thalassemia, sideroblastic anaemia, chronic haemolysis, lead induced anaemia, megaloblastic anaemia stemming from Vitamin B12 deficiency, pernicious anaemia, patients who show hypersensitivity to iron, patients receiving repeated blood transfusions.
Hypersensivity to any of the Vitamins, Lysine or Zinc.


With Food:
Absorption of iron salt is decreased when taken with tea. The absorption of zinc, although poor, may be decreased by food.
With other Drugs:
Dimercaprol – Iron supplements and dimercaprol may combine in the body to form a harmful chemical.
Acetohydroxamic acid (e.g., Lithostat) – Use with iron supplements may cause either medicine to be less effective.
Antacids – Use with iron supplements may make the iron supplement less effective; iron supplements should be taken 1 to 2 hours before or after antacids.
Use of iron supplements with Etidronate, Fluoroquinolones (e.g., Ciprofloxacin, Sparfloxacin, Lomefloxacin, Norfloxacin, Ofloxacin) or oral Tetracyclines may make these medicines less effective. Iron supplements may also decrease the absorption of Levodopa, Levothyroxine, Methyldopa or Penicillamine. Hence, iron supplements should be taken 2 hours before or after these medicines.
Zinc salts appear to reduce the effects of Penicillamine.

Adverse Effects

Gastrointestinal discomfort, vomiting, constipation, diarrhea, epigastric pain, black stools.

Dosage & Administration

One teaspoon (5 mL) daily or as directed by the physician.
Initially, epigastric pain, diarrhea and vomiting and may include metabolic acidosis, convulsions and coma after apparent recovery.
Speed is essential for effective treatment which is dependent upon removing excess iron from the alimentary tract prior to absorption. Initially an emetic should be given, followed by gastric lavage with 1% Sodium bicarbonate and oral administration of Dsferrioxamine to complex with residue.
Fluid loss may be corrected with IV Normal Saline or Dextrose solution.

Storage/Handling Recommendations

Store in a cool dark place. Shake well before use.
Keep out of reach of children.


Elder Pharmaceuticals Ltd, Elder House, Plot C-9, Dalia Ind. Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400 053, India.